Table 2 Comparison of changes in clinical parameters between abstainers and continued smokers
From: Effects of smoking cessation on endothelial function as assessed by flow-mediated total dilation
|  | Abstainers (n = 85) | Continued smokers (n = 33) | p-valuea | ||||
|---|---|---|---|---|---|---|---|
Baseline | Week 20 | Change | Baseline | Week 20 | Change | ||
Sex, % males | 69.4% (n = 59) |  |  | 81.8% (n = 27) |  |  |  |
Age, years | 59 ± 12 |  |  | 58 ± 11 |  |  |  |
BMI, kg/m2 | 23.7 ± 3.7 | 24.4 ± 3.8 | 0.7 ± 0.9 | 23.8 ± 3.8 | 24.3 ± 4.1 | 0.5 ± 0.8 | 0.157 |
Brinkman index | 817 ± 410 |  |  | 808 ± 378 |  |  |  |
Cigarettes per day | 22 ± 10 |  |  | 24 ± 10 |  |  |  |
CO concentration, ppm | 14.3 ± 9.7 | 1.9 ± 0.8 | -12.5 ± 9.8 | 18.2 ± 11.7 | 7.6 ± 5.0 | -10.8 ± 11.8 | 0.520 |
Hypertension | 34.1% (n = 29) |  |  | 45.4% (n = 15) |  |  |  |
SBP, mmHg | 117.7 ± 19.1 | 121.7 ± 17.1 | 4.0 ± 11.5 | 122.5 ± 13.7 | 121.8 ± 15.8 | -0.7 ± 11.2 | 0.048* |
DBP, mmHg | 74.6 ± 10.6 | 77.0 ± 9.7 | 2.4 ± 7.6 | 79.1 ± 7.8 | 79.2 ± 9.2 | 0.2 ± 7.7 | 0.161 |
HR, beats/min | 65.2 ± 10.9 | 66.5 ± 10.3 | 0.7 ± 7.6 | 68.2 ± 13.8 | 67.2 ± 13.5 | -0.3 ± 10.5 | 0.576 |
Diabetes mellitus | 23.5% (n = 20) |  |  | 24.2% (n = 8) |  |  |  |
HbA1c, % | 6.0 ± 0.9 | 6.2 ± 1.1 | 0.1 ± 0.6 | 6.0 ± 0.9 | 6.0 ± 1.3 | 0.0 ± 0.5 | 0.139 |
Fasting glucose, mg/dl | 100.7 ± 22.9 | 108.7 ± 33.5 | 7.9 ± 19.6 | 100.8 ± 12.5 | 103.3 ± 24.0 | 2.5 ± 17.8 | 0.180 |
Dyslipidemia | 71.8% (n = 61) |  |  | 60.6% (n = 20) |  |  |  |
HDL-C, mg/dl | 50.9 ± 15.7 | 54.0 ± 17.8 | 3.0 ± 9.6 | 49.1 ± 10.8 | 46.8 ± 11.3 | -2.3 ± 9.1 | 0.007** |
LDL-C, mg/dl | 116.0 ± 34.5 | 118.5 ± 38.5 | 2.3 ± 27.7 | 110.7 ± 28.6 | 111.1 ± 34.9 | 0.4 ± 27.1 | 0.741 |
Triglycerides, mg/dl | 153.0 ± 98.0 | 170.7 ± 206.9 | 17.6 ± 171.0 | 147.1 ± 103.7 | 167.1 ± 94.1 | 20.0 ± 119.1 | 0.941 |
eGFR, ml/min/1.73 m2 | 75.5 ± 21.1 | 74.6 ± 16.4 | -1.0 ± 16.1 | 77.1 ± 17.0 | 75.0 ± 25.8 | -2.1 ± 14.8 | 0.721 |
Dbase, mm | 4.04 ± 0.67 | 4.12 ± 0.65 | 0.08 ± 0.36 | 4.27 ± 0.66 | 4.29 ± 0.62 | 0.02 ± 0.43 | 0.459 |
L-FMC | 35.3% (n = 30) | 27.1% (n = 23) |  | 30.3% (n = 10) | 24.2% (n = 8) |  |  |
%L-FMC, % | -1.15 ± 1.90 | -0.88 ± 1.71 | 0.27 ± 2.19 | -1.20 ± 2.24 | -0.48 ± 1.11 | 0.76 ± 2.31 | 0.292 |
%FMD, % | 3.93 ± 1.91 | 4.89 ± 2.22 | 0.95 ± 2.28 | 4.35 ± 2.62 | 4.38 ± 2.91 | 0.06 ± 2.81 | 0.079 |
%FMTD, % | 5.08 ± 2.36 | 5.77 ± 2.91 | 0.69 ± 2.59 | 5.55 ± 2.96 | 4.86 ± 3.11 | -0.70 ± 2.03 | 0.007** |
baIMT, mm | 0.30 ± 0.08 | 0.31 ± 0.08 | 0.00 ± 0.06 | 0.32 ± 0.06 | 0.32 ± 0.06 | 0.00 ± 0.06 | 0.824 |