Table 1 Patient characteristics
Variables | Overall | Non-CA group | CA group | p value* |
|---|---|---|---|---|
(n = 341) | (n = 266) | (n = 75) | ||
Clinical variables | ||||
Age, years | 68 [56–76] | 66 [55–73] | 76 [72–83] | < 0.01 |
Male sex, n [%] | 218 [64] | 156 [59] | 62 [83] | < 0.01 |
BMI, kg/m2 | 23.6 [21.0-26.7] | 24.0 [21.4–27.2] | 22.0 [20.2–24.5] | < 0.01 |
BSA, m2 | 1.63 [1.51–1.78] | 1.65 [1.51–1.82] | 1.58 [1.47–1.68] | < 0.01 |
Systolic BP, mmHg | 130 [113–143] | 132 [118–148] | 112 [98–134] | < 0.01 |
Diastolic BP, mmHg | 71 [62–81] | 73 [65–82] | 62 [55–75] | < 0.01 |
Heart rate, bpm | 67 [60–77] | 65 [58–76] | 74 [66–83] | 0.01 |
AF, n [%] | 83 [24] | 61 [23] | 22 [29] | 0.25 |
Paroxysmal type | 54 [16] | 38 [14] | 16 [21] | |
Permanent type | 29 [9] | 23 [9] | 6 [8] | |
Medications, n, % | ||||
β blocker | 179 [52] | 155 [58] | 24 [32] | < 0.01 |
ACEi/ARB | 151 [44] | 118 [44] | 33 [44] | 0.96 |
MRA | 80 [23] | 54 [20] | 26 [35] | 0.01 |
Loop diuretics | 128 [38] | 74 [28] | 54 [72] | < 0.01 |
Serum markers | ||||
Hemoglobin, g/dL | 13.4 [11.9–14.7] | 13.5 [12.1–14.9] | 12.6 [11.4–14.1] | 0.01 |
eGFR, mL/min/1.73 m2 | 60.5 [45.9–73.4] | 62.5 [49.1–74.4] | 46.5 [40.8–61.6] | < 0.01 |
Albumin, mg/L | 4.0 [3.6–4.3] | 4.1 [3.7–4.3] | 3.8 [3.3–4.1] | < 0.01 |
Sodium, mmol/L | 140 [139–142] | 140 [139–142] | 139 [137–141] | < 0.01 |
BNP, pg/mL | 146 [59–369] | 111 [45–269] | 290 [162–628] | < 0.01 |