Variables | Total LBBB N = 111 | LBBB with GLS>-20% N = 52 | LBBB with GLS ≤ -20% N = 59 | P- values |
---|---|---|---|---|
Demographics | ||||
 Age, years | 61.1 ± 10.7 | 61.0 ± 8.8 | 61.2 ± 12.2 | 0.92 |
 Female, n (%) | 59 (53.2) | 25 (48.1) | 34 (57.6) | 0.35 |
 Current smoking, n (%) | 29 (26.1) | 11 (21.2) | 18 (30.5) | 0.29 |
 Body surface area, m2 | 1.72 ± 0.18 | 1.70 ± 0.17 | 1.74 ± 0.20 | 0.27 |
 Heart rate, beats/min | 76.0 ± 11.4 | 75.9 ± 11.0 | 76.0 ± 11.8 | 0.97 |
 Systolic blood pressure, mmHg | 129.35 ± 21.13 | 130.48 ± 19.07 | 128.18 ± 23.52 | 0.19 |
 Diastolic blood pressure, mmHg | 78.86 ± 12.41 | 79.81 ± 10.57 | 77.28 ± 13.17 | 0.13 |
Echocardiographic | ||||
 LV end-diastolic diameter, mm | 51.13 ± 5.74 | 52.65 ± 6.17 | 49.80 ± 5.02 | 0.01 |
 Interventricular septum, mm | 9.38 ± 1.05 | 9.47 ± 0.91 | 9.31 ± 1.08 | 0.31 |
 Posterior wall thickness, mm | 9.02 ± 1.01 | 9.10 ± 1.03 | 8.93 ± 0.94 | 0.19 |
 Relative wall thickness | 0.36 ± 0.04 | 0.35 ± 0.04 | 0.36 ± 0.03 | 0.22 |
 LV mass, g | 172.06 ± 26.73 | 181.17 ± 27.46 | 161.92 ± 23.13 | 0.01 |
 LV mass index, g/m2 | 101.08 ± 15.74 | 107.54 ± 16.35 | 94.08 ± 13.31 | 0.02 |
 Geometry | ||||
  Normal geometry | 78 | 24 | 54 | < 0.001 |
  Eccentric hypertrophy | 28 | 24 | 4 | < 0.001 |
  Concentric remodeling | 2 | 1 | 1 | 1.0 |
  Concentric hypertrophy | 3 | 3 | 0 | 0.1 |
 LV end-diastolic volume, mL | 107.46 ± 27.67 | 114.79 ± 25.85 | 101.01 ± 27.81 | 0.01 |
 LVEF, % | 60.03 ± 5.65 | 57.15 ± 5.26 | 62.56 ± 4.73 | < 0.001 |
 LV GLS, % | -20.00 ± 2.57 | -17.70 ± 1.26 | -22.02 ± 1.47 | < 0.001 |
 LV septal longitudinal strain, % | -16.83 ± 2.41 | -15.52 ± 1.22 | -18.07 ± 1.31 | < 0.001 |
 LV lateral longitudinal strain, % | -23.08 ± 2.52 | -19.79 ± 1.30 | -25.88 ± 1.51 | < 0.001 |
 LAVI, mL/m2 | 32.90 ± 11.20 | 33.56 ± 10.67 | 32.37 ± 11.67 | 0.59 |
 Mitral E, m/s | 0.62 ± 0.13 | 0.62 ± 0.14 | 0.63 ± 0.11 | 0.71 |
 Mitral E/A | 0.77 ± 0.26 | 0.73 ± 0.18 | 0.81 ± 0.31 | 0.17 |
 Mitral septal E’, cm/s | 5.12 ± 1.45 | 4.55 ± 1.19 | 5.59 ± 1.49 | < 0.001 |
 Mitral lateral E’,cm/s | 8.26 ± 1.40 | 7.73 ± 0.86 | 8.69 ± 1.60 | < 0.001 |
 Mitral average E’,cm/s | 6.80 ± 0.95 | 6.28 ± 0.66 | 7.21 ± 0.96 | < 0.001 |
 Mitral average E/ E’ | 10.06 ± 2.55 | 10.76 ± 2.64 | 9.46 ± 2.32 | 0.02 |
 Ts-SD, ms | 59.18 ± 14.25 | 66.62 ± 13.65 | 52.61 ± 11.29 | < 0.001 |
 Ts-Dif (ms) | 188.21 ± 63.01 | 196.25 ± 66.25 | 180.25 ± 59.80 | < 0.001 |
 IVMD (ms) | 60.50 ± 16.08 | 68.58 ± 16.12 | 52.45 ± 16.01 | < 0.001 |