Relationship between electrocardiographic characteristics and subclinical left ventricular systolic dysfunction in isolated left bundle branch block patients

Table 3 Univariable and multivariable regression analysis of the ECG characteristics for LVSD in LBBB_pEF

Variables	Univariable		Multivariable^&
Variables	OR (95% CI)	P-value	OR (95% CI)	P-value
Heart rate	1.00 (0.97–1.03)	0.97
QRS duration	1.08 (1.04–1.12)	< 0.001	1.07 (1.02–1.13)	0.007
PR duration	1.00 (0.98–1.02)	0.94
QTC duration	1.01 (1.00-1.02)	0.14	1.01 (0.99–1.03)	0.47
Notching R-wave in leads I and aVL	1.69 (0.77–3.74)	0.19
Notching R-wave in leads V5 and V6	1.57 (0.73–3.36)	0.25
Notching R-wave in leads inferior	0.66 (0.31–1.40)	0.28
Number of leads with notching R-wave	1.10 (0.95–1.28)	0.20
Presence of QS	0.29 (0.13–0.65)	0.002	0.19 (0.08–0.57)	0.003
Discordant LBBB*	0.22 (0.10–0.50)	< 0.001	0.32 (0.11–0.91)	0.03

Abbreviations: LBBB left bundle branch block, LVSD left ventricle systolic disfunction
^& Forward stepwise logistic regression (likelihood ratio) for identifying subclincial LV systolic dysfunction in isolated LBBB with preserved LVEF by ECG characteristic factors (including QRS duration, PR duration, QTC duration, Notching R-wave in different LV wall, Presence of QS, discordant LBBB), corrected for age, sex and LVEF
* Discordant LBBB T-wave orientation discordant with QRS complex in leads I, V5, and V6

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