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Table 2 Twin pregnancies in PA/IVS fetuses

From: Prenatal diagnosis of pulmonary atresia with intact ventricular septum: a single-center study in China

Case

chorionic and amniotic

Fetus with PA/IVS(Fetus A)

Fetus B

Characteristics of the case

Outcome

1

MCDA

PA/IVS, severe tricuspid regurgitation

(-)

/

Born at 34+ 4 weeks, Fetus A: 2340 g, Apgar 9-10-10, postnatal echocardiography: PA/IVS and restricted tricuspid valve opening with severe regurgitation. Fetus B: 2010 g, Apgar 7-10-10, postnatal echocardiography: patent ductus arteriosus and patent foramen ovale.

2

MCDA

PA/IVS, severe tricuspid regurgitation

VSD, ARSA

Reversed DV a-wave of two fetuses during early pregnancy

Termination

3

MCDA

PA/IVS, severe tricuspid regurgitation, increased cardiothoracic ratio, Reversed DV a-wave, ascites, excessive amniotic fluid

(-)

/

Born at 31+ 6 weeks, Fetus A: 1470 g, Apgar 10, postnatal echocardiography: PA/IVS, patent ductus arteriosus (left-to-right shunt), patent foramen ovale, Atrial septal defect, mitral regurgitation +-++, tricuspid regurgitation ++++, and the estimated systolic pressure of the pulmonary artery was 53mmHg; Fetus B, 1410 g, Apgar 10.

4

MCDA

Increased cardiothoracic ratio, severe tricuspid regurgitation, PA/IVS, Reversed DV a-wave, abnormal pulsation of the umbilical vein

Progression to PA/IVS, severe tricuspid regurgitation with progression of gestational weeks

TTTS, PA/IVS with increasing gestational weeks

Fetus A died in utero. Fetus B was born at 27w, 915 g, Apgar 10, Postnatal Echocardiography: PA/IVS, severe tricuspid regurgitation, patent ductus arteriosus (left-to-right shunt), patent foramen ovale, and the estimated systolic pressure of the pulmonary artery was 32mmHg

5

MCMA

PA/IVS, severe tricuspid regurgitation

(-)

/

Termination

6

DCDA

PA/IVS, right ventricular dysplasia, VCAC

(-)

Detected at 13 weeks of gestation

Selective reduction of fetus A, full-term delivery of fetus B